Benzoimidazoles as prolyl hydroxylase inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 403/04 (2006.01) A61K 31/4184 (2006.01) A61P 7/06 (2006.01) A61P 9/10 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2722772

The present invention is directed to benzoimidazole compounds of the formula (1) and enantiomers, diastereomers, racemates, and pharmaceutically acceptable salts thereof. Compounds of the present invention are useful in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions modulated by prolyl hydroxylase activity.

La présente invention concerne des composés benzoimidazole de formule (1) et leurs énantiomères, diastéréomères, racémates, et sels pharmaceutiquement acceptables. Les composés de la présente invention sont utiles dans des compositions pharmaceutiques et des méthodes de traitement détats pathologiques, de troubles et daffections modulés par lactivité de la prolyl hydroxylase.

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