Benzoimidazolyl-parazine compounds for inflammation and...

C - Chemistry – Metallurgy – 07 – D

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C07D 241/00 (2006.01) A61K 31/497 (2006.01) C07D 241/02 (2006.01)

Patent

CA 2645434

The invention relates to compounds of structural formula (I) or (III) or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof, wherein ring A, X1, X2, X3, X5, R1, R4, Y, Z, L, m and n are defined herein. These compounds are useful as immunosuppressive agents and for treating and preventing inflammatory conditions, allergic disorders, and immune disorders.

La présente invention concerne des composés de formule (I) ou (III) ou un sel, solvate, clathrate, ou promédicament de celui-ci pharmaceutiquement acceptable, dans lesquelles le noyau A, X1, X2, X3, X5, R1, R4, Y, Z, L, m et n sont tels que définis dans la description. Ces composés sont utiles en tant qu'agents immunosuppresseurs et pour traiter et prévenir des conditions inflammatoires, des troubles allergiques, et des troubles immunitaires.

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