Benzomorphan compounds

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 471/08 (2006.01) A61K 31/14 (2006.01) A61K 31/439 (2006.01) A61P 1/10 (2006.01)

Patent

CA 2707174

The invention relates to Benzomorphan Compounds of Formula (I): wherein X, R1, R2, R3, R4, and R5 are as defined herein. These compounds are useful for treating constipation preferably constipation caused by mu-opioid agonist therapy.

La présente invention concerne des composés à base de benzomorphane de formule (I), dans laquelle : X, R1, R2, R3, R4, et R5 sont tels que définis sans la description. Ces composés sont utiles pour le traitement de la constipation, notamment la constipation provoquée par la thérapie par des agonistes de mu-opioïdes.

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