C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 15/203 (2006.01) A61K 31/70 (2006.01) A61P 9/10 (2006.01)
Patent
CA 2395557
The invention concerns (i) [4-(4-cyanobenzyl)phenyl].alpha.-D-glycopyranosides of formula (I) wherein: the group .alpha.-D-glycopyranosyl R represents a .alpha.-D-glycopyranosyl, .alpha.-D-galactopyranosyl, .alpha.-D- mannopyranosyl, .alpha.-D-arabinopyranosyl, .alpha.-D-lyxopyranosyl, or .alpha.-D-ribopyranosyl group; (ii) their esters resulting from the esterification of at least a OH function of each pyranosyl group with a C2-C4 alkanoic or a cycloalkanoic acid, as novel industrial products. Said novel [4- (4-cyanobenzyl)phenyl].alpha.- D-glycopyranosides are useful in therapy for fighting against atheromatous plaque.
La présente invention concerne en tant que produits industriels nouveaux: (i) les [4-(4-cyanobenzoyl)phényl].alpha.-D-glycopyranosides de formule (I): dans laquelle le groupe .alpha.-D-glycopyranosyle R représente un groupe .alpha.-D-glycopyranosyle, .alpha.-D-galactopyranosyle, .alpha.-D-mannopyranosyle, .alpha.-D-arabinopyranosyle, .alpha.-D-lyxopyranosyle, ou .alpha.-D-ribopyranosyle; et, (ii) leurs esters résultant de l'estérification d'au moins d'une fonction OH de chaque groupe glycopyranosyle par un acide alcanoïque ou cycloalcanoïque en C¿2?-C¿4?. Ces nouveaux [4-(4-cyanobenzoyl)phényl] .alpha.-D-glycopyranosides sont utiles en thérapeutique vis-à-vis de la plaque d'athérome.
Lebreton Luc
Legendre Christiane
Samreth Soth
Fournier Industrie Et Sante
Lebreton Luc
Legendre Christiane
Ogilvy Renault
Samreth Soth
LandOfFree
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