Benzopyran derivative

C - Chemistry – Metallurgy – 07 – D

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C07D 311/68 (2006.01) A61K 31/35 (2006.01) A61K 31/38 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) C07D 311/96 (2006.01) C07D 405/12 (2006.01) C07D 407/12 (2006.01) C07D 409/12 (2006.01)

Patent

CA 2086322

- 92 - A B S T R A C T Disclosed is a benzopyrane derivative represented by the general formula given below or a phar- macuetically acceptable salt thereof: Image (I) where R1, etc. are as defined in the specification. The compound permits activating the potassium channel and produces a substained effect of reducing the blood pressure and, thus, to produce the action of relaxing the capillary vessels. It follows that the particular compound is useful as a therapeutic agent of hypertension. The compound also permits selectively increasing the coronary blood stream and, thus, is use- ful as a therapeutic agent of cardiovascular disorder such as angina pectoris and heart failure.

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