Benzopyran derivatives substituted with secondary amines...

Details Benzopyran derivatives substituted with secondary amines... Benzopyran derivatives substituted with secondary amines...

C - Chemistry, Metallurgy

07

D

C07D 405/12 (2006.01) A61K 31/41 (2006.01)

Patent

CA 2481707

The present invention relates to benzopyran derivatives substituted with secondary amines having tetrazole, method for preparing thereof and pharmaceutical compositions containing them. The compounds of the present invention can be used for protecting neuronal cells and brain damage; antioxidation; inhibiting NO generation; protecting heart; suppressing angiogenesis; protecting preserving organs such as kidney, heart and tissue, and protecting organs in major cardiovascular surgery.

L'invention concerne des dérivés de benzopyrane substitués au moyen d'amines secondaires comprenant un tétrazole, leur procédé de préparation, et des compositions pharmaceutiques contenant lesdits dérivés. Les composés de l'invention peuvent être utilisés pour protéger les cellules neuronales et réduire les lésions cérébrales; pour inhiber l'oxydation et la génération d'oxyde nitrique; pour protéger le coeur; pour supprimer l'angiogénèse; pour préserver des organes tels que les reins, le coeur et des tissus et protéger des organes au cours d'une chirurgie cardio-vasculaire principale.

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