C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 311/66 (2006.01) A61K 31/353 (2006.01) A61P 3/10 (2006.01)
Patent
CA 2423141
A class of benzopyrancarboxylic acid derivatives comprises compounds that are potent agonists of PPAR alpha and/or gamma, and are therefore useful in the treatment, control or prevention of non-insulin dependent diabetes mellitus (NIDDM), hyperglycemia, dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, atherosclerosis, obesity, vascular restenosis, inflammation, and other PPAR alpha and/or gamma mediated diseases, disorders and conditions.
Cette invention concerne une classe de dérivés de l'acide benzopyrancarboxylique comprenant des composés qui sont des agonistes puissance de du récepteur PPAR alpha et/ou gamma, et qui permettent donc bien de traiter, combattre ou prévenir le diabète sucré non insulinodépendant, l'hyperglycémie, la dyslipidémie, l'hyperlipidémie, l'hypercholesterolémie, l'hypertriglyceridémie, l'athérosclerose, l'obésité, la resténose vasculaire, les troubles inflammatoires et autres maladies, troubles et états pathologiques induits par le récepteur PPAR alpha et/ou gamma.
Boueres Julia K.
Desai Ranjit C.
Koyama Hiroo
Miller Daniel J.
Sahoo Soumya P.
Gowling Lafleur Henderson Llp
Merck & Co. Inc.
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