C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 413/12 (2006.01) A61K 31/335 (2006.01) A61K 31/352 (2006.01) A61K 31/423 (2006.01) A61K 45/06 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) A61P 9/10 (2006.01) C07D 311/66 (2006.01) C07D 407/12 (2006.01)
Patent
CA 2427610
A class of benzopyrancarboxylic acid derivatives comprises compounds that are potent agonists of PPAR alpha and/or gamma, and are therefore useful in the treatment, control or prevention of non-insulin dependent diabetes mellitus (NIDDM), hyperglycemia, dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, atherosclerosis, obesity, vascular restenosis, inflammation, and other PPAR alpha and/or gamma mediated diseases, disorders and conditions.
Catégorie de dérivé d'acide benzopyranocarboxylique comprenant des composés représentant des agonistes puissants de PPAR alpha et/ou gamma, et étant, de ce fait, utile pour le traitement, le contrôle ou la prévention du diabète sucré non-insulino-dépendant (NIDDM), de l'hyperglycémie, de la dyslipidémie, de l'hyperlipidémie, de l'hypercholestérolémie, de l'hyertriglycéridémie, de l'athérosclérose, de l'obésité, de la resténose vasculaire, de l'inflammation ou d'autres troubles ou maladies dans lesquelles PPAR alpha et/ou gamma joue un rôle.
Boueres Julia K.
Desai Ranjit C.
Koyama Hiroo
Miller Daniel J.
Sahoo Soumya P.
Gowling Lafleur Henderson Llp
Merck & Co. Inc.
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