Benzopyranone-.beta.-d-thioxylosides their method of...

C - Chemistry – Metallurgy – 07 – D

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C07D 409/12 (2006.01) A61K 31/38 (2006.01) C07D 311/04 (2006.01) C07D 311/12 (2006.01) C07D 311/14 (2006.01) C07D 311/16 (2006.01) C07D 311/18 (2006.01) C07D 311/22 (2006.01) C07D 311/86 (2006.01) C07H 17/04 (2006.01) C07H 17/07 (2006.01) C07H 17/075 (2006.01)

Patent

CA 2024476

The present invention relates, by way of novel industrial products, to the benzopyranone-.beta.-D-thioxyloside compounds of the formula (see formula I) in which: - one of the substituents R or R' is an oxygen atom double-bonded to the corresponding cyclic carbon atom and the other is a group R1, - the symbol ~~~ represents a double bond conjugated to the CO group provided by one of the substituents R or R', - X is a sulfur atom or an oxygen atom, - R1 and R2, which are identical or different, are each a hydrogen atom, a C1-C4 alkyl group, a halogen atom, a trifluoromethyl group or a phenyl group, it being possible for R1 and R2, taken together, to form a 7,8,9,10-tetrahydrodibenzo[b,d]pyran-6-one group or a 1,2,3,4-tetrahydro-9H-xanthen-9-one group with the benzopyranone group to which they are bonded, and - Y is the hydrogen atom or an aliphatic acyl group. These compounds are useful in therapy, especially as venous antithrombotics.

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