Benzopyrans and related ltb4 antagonists

Details Benzopyrans and related ltb4 antagonists Benzopyrans and related ltb4 antagonists

C - Chemistry, Metallurgy

07

D

C07D 311/22 (2006.01) A61K 31/19 (2006.01) A61K 31/35 (2006.01) A61K 31/47 (2006.01) C07C 45/46 (2006.01) C07C 59/54 (2006.01) C07C 59/64 (2006.01) C07C 255/13 (2006.01) C07D 209/36 (2006.01) C07D 215/233 (2006.01) C07D 335/06 (2006.01) C07D 405/02 (2006.01) C07D 405/08 (2006.01) C07D 405/12 (2006.01) C07D 407/02 (2006.01) C07D 409/02 (2006.01) C07D 409/06 (2006.01)

Patent

CA 2117349

Benzopyran and other benzo-fused leukotriene B4 antagonists have formula (I) wherein A, n, R1, R2 and R3 are as defined herein. The compounds of formula (I) wherein R1 is c-substituted CR4R5-COOR13 may be prepared from the corresponding c-substituted CF3SO3 compound by reaction with a trimethylsilyl ketene acetal.

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