Benzopyranylpyrrolinone derivatives

Details Benzopyranylpyrrolinone derivatives Benzopyranylpyrrolinone derivatives

C - Chemistry, Metallurgy

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C07D 311/68 (2006.01) A61K 31/40 (2006.01) C07D 311/70 (2006.01) C07D 405/04 (2006.01)

Patent

CA 2005031

26510-FF ABSTRACT OF THE DISCLOSURE Compounds of the formula Image (I) wherein: R1 is-cyano or nitro; R2 and R3 are independently hydrogen or lower alkyl; and R4 is alkyl; alkenyl; optionally substituted phenyl or phenyl lower alkyl; -(CH2)mOR2 or -(CH2)mN(R2)2; wherein m is an integer of 1-5 and R2 is as defined above; or a pharmaceutically acceptable ester or acid addition salt thereof; are smooth muscle relaxants, particularly useful in the treatment of hypertension.

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