Benzothiazin-3-one compound and intermediate therefor

Details Benzothiazin-3-one compound and intermediate therefor Benzothiazin-3-one compound and intermediate therefor

C - Chemistry, Metallurgy

07

D

C07D 279/16 (2006.01) A61K 31/5415 (2006.01) A61P 29/00 (2006.01) A61P 43/00 (2006.01) C07C 59/64 (2006.01) C07C 69/734 (2006.01) C07C 205/56 (2006.01)

Patent

CA 2560664

A medicine which contains as an active ingredient a benzothiazin-3-one compound represented by the formula (1): (wherein n is 3 or 4; R represents ethyl or hydrogen; and R1 represents halogeno, alkoxy, haloalkyl, or haloalkoxy) or a pharmaceutically acceptable salt thereof. It is useful as a therapeutic or preventive agent for arthrosis deformans, chondrodegenerative diseases such as chronic articular rheumatism, cancers, gingivitis, etc. Also provided are an intermediate for the compound and a process for producing the compound.

Un médicament qui contient en tant qu'ingrédient actif un composé de benzothiazine-3-one représenté par la formule (1) : (A) position-2 (1) (dans laquelle n vaut 3 ou 4, R représente un éthyle ou de l'hydrogène, et R?1¿ représente un groupement halogeno, alkoxy, haloalkyle, ou haloalkoxy) ou un sel de ceux-ci acceptable d'un point de vue pharmaceutique. Il est utile en tant qu'agent thérapeutique ou préventif pour l'arthrosis deformans, les maladies chondro-dégénératives telles que le rhumatisme articulaire chronique, des cancers, des gingivites, etc. Un produit intermédiaire et un procédé pour fabriquer le composé sont également prévus pour le composé.

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