C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 277/62 (2006.01) A23K 1/16 (2006.01) A61K 31/42 (2006.01) A61K 31/425 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) C07D 263/54 (2006.01) C07D 263/56 (2006.01) C07D 277/64 (2006.01) C07D 277/66 (2006.01) C07D 277/68 (2006.01) C07D 277/74 (2006.01) C07D 277/76 (2006.01) C07D 413/00 (2006.01) C07D 417/00 (2006.01) C07D 417/04 (2006.01) C07D 417/12 (2006.01)
Patent
CA 2217860
The invention concerns benzothiazoles and benzoxazoles of generale formula (I), in which R1 to R3, X, Z and n are as defined in claim 1, their enantiomers, diastereomers and salts thereof, in particular physiologically tolerated acid addition salts, which exhibit biosynthesis of cholesterol. The invention also concerns drugs containing these compounds, their use and methods of preparing them.
L'invention concerne des benzothiazoles et des benzoxazoles de la formule générale (I) dans laquelle R?1¿ à R?3¿, X, Z et n correspondent à la définition donnée dans la revendication 1, leurs énantiomères, leurs diastéréomères et leurs sels, notamment leurs sels d'addition d'acide physiologiquement tolérables, qui possèdent des propriétés précieuses et ont notamment un effet inhibiteur sur la biosynthèse du cholestérol. L'invention concerne par ailleurs des médicaments contenant lesdits composés, leur utilisation et des procédés permettant de les préparer.
Budzinski Ralph-Michael
Eisele Bernhard
Hallermayer Gerhard
Hurnaus Rudolf
Maier Roland
Dr. Karl Thomae Gesellschaft Mit Beschrankter Haftung
Fetherstonhaugh & Co.
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