Benzothiazoles having histamine h3 receptor activity

Details Benzothiazoles having histamine h3 receptor activity Benzothiazoles having histamine h3 receptor activity

C - Chemistry, Metallurgy

07

D

C07D 277/82 (2006.01) A61K 31/496 (2006.01) A61K 31/4985 (2006.01) C07D 263/58 (2006.01) C07D 413/04 (2006.01) C07D 417/04 (2006.01) C07D 417/06 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2645581

Certain novel benzothiazoles and benzoxazoles, e.g., 2-(piperazin-1-yl)benzothiazoles and 2-(piperazin-1-yl)benzoxazoles, optionally substituted in the 3 and/or 4 positions of the piperazine rings,! of the general formula (l): having histamine H3 antagonistic activity can be used in pharmaceutical compositions.

L'invention concerne certains nouveaux benzothiazoles et benzoxazoles, par exemple les 2-(pipérazin-1-yl)benzothiazoles et les 2-(pipérazin-1-yl)benzoxazoles, éventuellement substitués au niveau des positions 3 et/ou 4 des cycles pipérazine, de formule générale (1), présentant une activité antagoniste sur le récepteur H3 de l'histamine pouvant être utilisés dans des compositions pharmaceutiques.

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