Benzothienopyridines for use as inhibitors of eg5 kinesin

Details Benzothienopyridines for use as inhibitors of eg5 kinesin Benzothienopyridines for use as inhibitors of eg5 kinesin

C - Chemistry, Metallurgy

07

D

C07D 495/14 (2006.01) A61K 31/437 (2006.01) A61P 35/00 (2006.01) C07D 471/14 (2006.01)

Patent

CA 2576619

Compounds of a certain formula I, in which R1, R2, R3, R4 and X have the meanings indicated in the description, are novel effective compounds with Eg5 inhibitory, anti-proliferative and/or apoptosis inducing activity.

L'invention concerne des composés représentés par la formule générale (I), dans laquelle R1, R2, R3, R4 et X désignent des éléments définis dans la description de la présente demande. Ces composés présentent une activité inhibant la kinésine Eg5, une activité anti-proliférative et/ou une activité induisant l'apoptose.

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