Benzothiepin derivatives, their production and use

Details Benzothiepin derivatives, their production and use Benzothiepin derivatives, their production and use

C - Chemistry, Metallurgy

07

D

C07D 417/12 (2006.01) A61K 31/55 (2006.01) C07D 211/88 (2006.01) C07D 233/74 (2006.01) C07D 263/44 (2006.01) C07D 277/04 (2006.01) C07D 295/135 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2339662

Compounds represented by general formula (I) or salts thereof, which exhibit osteogenesis- and chondrogenesis-accelerating effects and are thus useful as drugs; and prodrugs of both: wherein A is an optionally substituted benzene ring; R1 is an optionally substituted nonaromatic heterocyclic group; R2 and R3 are each hydrogen or optionally substituted hydrocarbyl; and n is an integer of 0 to 3.

L'invention concerne des composés représentés par la formule générale (I) ou bien des sels de ceux-ci, lesquels présentent des effets accélérant l'ostéogenèse et la chondrogénèse et lesquels sont utiles en tant que médicaments; et des promédicaments ayant les deux effets, formule dans laquelle A représente un cycle benzène facultativement substitué; R?1¿ représente un groupe hétérocyclique non aromatique facultativement substitué; R?2¿ et R?3¿ représentent chacun hydrogène ou hydrocarbyle facultativement substitué; et n représente un nombre entier de 0 à 3.

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