Benzothiepines having activity as inhibitors of ileal bile...

Details Benzothiepines having activity as inhibitors of ileal bile... Benzothiepines having activity as inhibitors of ileal bile...

C - Chemistry, Metallurgy

07

D

C07D 337/08 (2006.01) A61K 31/38 (2006.01) C07C 319/14 (2006.01) C07C 323/18 (2006.01) C07D 409/10 (2006.01) C07D 409/12 (2006.01) C07D 487/08 (2006.01) C07F 9/6553 (2006.01) C07K 5/06 (2006.01) C07K 5/068 (2006.01) C07C 323/12 (2006.01)

Patent

CA 2336315

Novel benzothiepines, derivatives, and analogs thereof; methods of preparing such compounds; pharmaceutical compositions containing such compounds; and methods of using these compounds and compositions in the preparation of a medicament, particularly medicaments for use in the prophylaxis and treatment of hyperlipidemic conditions such as those associated with atherosclerosis or hypercholesterolemia, in mammals.

L'invention concerne des nouvelles benzothiépines, des dérivés et analogues de celles-ci, des procédés de préparation de tels composés, des compositions pharmaceutiques contenant ces composés ainsi que des méthodes d'utilisation de ces composés et compositions dans la préparation d'un médicament; elle concerne notamment des médicaments utiles dans la prophylaxie et le traitement d'états hyperlipidémiques, tels ceux associés à l'athérosclérose ou l'hypercholestérolémie, chez des mammifères.

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