Benzothiophene derivatives useful in therapy

C - Chemistry – Metallurgy – 07 – D

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C07D 333/70 (2006.01) A61K 31/38 (2006.01) A61K 31/41 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) C07D 409/06 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01) C07D 417/12 (2006.01) C07D 471/04 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2255165

Compounds of formula I, Image wherein X represents O or S(O)m; R1 and R2 independently represent phenyl, naphthyl or heteroaryl; each of which is optionally fused and optionally substituted; Y represents a bond, O, (CH2)n, O(CH2)n, (CH2)n O, or CH(C1-6 alkyl)O; R3 represents H or C1-6 alkyl; m represents 0, 1, or 2; and n represents 1, or 2; and pharmaceutically acceptable salts thereof, are useful in therapy, in particular in the treatment of restenosis, renal failure and pulmonary hypertension.

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