Benzothiophenes, formulations containing same, and methods

Details Benzothiophenes, formulations containing same, and methods Benzothiophenes, formulations containing same, and methods

C - Chemistry, Metallurgy

07

D

C07D 333/58 (2006.01) A61K 31/445 (2006.01) C07D 333/56 (2006.01)

Patent

CA 2250191

This invention provides compounds of formula (I) and pharmaceutically acceptable salts an solvates thereof, characterized that the compound is in particulate form and has a specific size range. The present invention further provides pharmaceutical compositions containing or formulated using compounds of formula (I), and the use of such compounds for alleviating human pathologies, including osteoporosis, serum lipid lowering, and breast cancer.

Composés de formule (I) et sels et solvats de ceux-ci, acceptables sur le plan pharmaceutique, caractérisés par le fait que le composé se présente sous forme particulaire et possède une fourchette granulométrique spécifique. L'invention porte aussi sur des compositions pharmaceutiques comprenant des composés de la formule (I) ou formulées selon ceux-ci, et sur l'emploi de tels composés pour soulager des pathologies humaines, dont l'ostéoporose, la baisse des lipides sériques et le cancer du sein.

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