C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/301, 260/303
C07D 413/04 (2006.01) C07D 417/04 (2006.01) C07D 487/04 (2006.01) C07D 498/04 (2006.01)
Patent
CA 1336976
Compounds of formula III: Image (III) wherein R1 is a 5- or 6-membered aromatic heterocyclic group; and R4 and R5 each independently signify hydrogen, halogen, trifluoromethyl, cyano, nitro, amino or lower alkyl; are useful intermediates in a novel process for the preparation of a class of pharmacologically active compounds of formula I: Image (I) wherein R1, R4 and R5 are as defined above; and R3 represents hydrogen or lower alkyl.
613616
Houghton Peter G.
Wright Stanley H. B.
Merck Sharp & Dohme Limited
Swabey Ogilvy Renault
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