C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 265/36 (2006.01) A61K 31/538 (2006.01) A61K 31/5415 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) C07C 229/34 (2006.01) C07C 229/42 (2006.01) C07D 279/16 (2006.01)
Patent
CA 2463686
The present invention relates to novel antidiabetic, hypolipidemic, antiobesity and hypocholesterolemic compounds of formula (I) their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them, to a process for preparing such compounds. More particularly, the present invention relates to novel alkyl carboxylic acids of the general, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them, to a process for preparing such compounds. The present invention also relates to processes for the preparation of the compounds of formula (I), novel intermediates, processes for their preparation, their use in the preparation of the above said compounds and their use as antidiabetic, hypolipidemic, antiobesity and hypocholesterolemic compounds.
L'invention concerne des composés anti-diabétiques, hypolipidémiques, anti-obésité et hypocholestérolémiques, représentés par la formule (I), y compris leurs dérivés, analogues, formes tautomères, stéréoisomères, polymorphes, sels pharmaceutiquement acceptables, solvates pharmaceutiquement acceptables et compositions pharmaceutiquement acceptables contenant ces composés. L'invention concerne également un procédé d'élaboration correspondant. Plus précisément, l'invention concerne de façon générale des acides alkylcarboxyliques, y compris leurs dérivés, analogues, formes tautomères, stéréoisomères, polymorphes, sels pharmaceutiquement acceptables, solvates pharmaceutiquement acceptables et compositions pharmaceutiquement acceptables contenant ces composés. L'invention concerne également un procédé d'élaboration correspondant. L'invention concerne enfin des procédés relatifs à l'élaboration des composés représentés par la formule (I), des intermédiaires, des procédés d'élaboration correspondants, l'utilisation de ces intermédiaires pour l'élaboration des composés cités, et leur utilisation comme composés anti-diabétiques, hypolipidémiques, anti-obésité et hypocholestérolémiques.
Bhuniya Debnath
Chakrabarti Ranjan
Das Saibal Kumar
Iqbal Javed
Madhavan Gurram Ranga
Dr. Reddy's Laboratories Ltd.
Marks & Clerk
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