Benzoxazine derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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260/244.7, 260/2

C07D 498/04 (2006.01) C07C 205/37 (2006.01) C07D 265/36 (2006.01) C07D 498/06 (2006.01)

Patent

CA 1167840

ABSTRACT OF THE DISCLOSURE Pyrido[1,2,3-de][1,4]benzoxazine derivatives are described having the formula (I) Image (I) wherein X is a halogen atom, R is a hydrogen atom or an alkyl group of 1 to 6 carbon atoms and Z represents mono-substituted, di- substituted or cyclic-substituted amino group which may contain a hetero atom and may have a substituent such as hydroxy, alkyl having 1 to 6 carbon atoms, amino, hydroxy- alkyl having 1 to 6 carbon atoms or mono- or di-alkylamino having 1 to 6 carbon atoms in each alkyl moiety and the pharmaceutically acceptable salt thereof, having anti- bacterial activity.

385046

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