Benzoxazinone and benzothiazinone derivatives endowed with...

Details Benzoxazinone and benzothiazinone derivatives endowed with... Benzoxazinone and benzothiazinone derivatives endowed with...

C - Chemistry, Metallurgy

07

D

C07D 265/22 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) C07D 279/08 (2006.01) C07D 413/04 (2006.01) C07D 417/04 (2006.01)

Patent

CA 2056814

Benzoxazinone and benzothiazinone derivatives of formula Image I wherein R represents hydrogen, (C2-6)alkyl, (C5-7)cycloalkyl, phenyl, substituted phenyl; R1 and R2 independently represent hydrogen, halogen, (C1-4)alkyl, (C1-4)alkoxy or trifluoromethyl; X is oxigen or sulfur; Y is (C2-6)alkylene or (C5-7)cycloalkylene; and salts therewith of pharmaceutically acceptable acids. The compounds possess cardiovascular activity with high specificity for the coronary district.

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