C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 413/04 (2006.01) A61K 31/553 (2006.01) A61P 31/04 (2006.01) C07D 413/14 (2006.01)
Patent
CA 2642406
The present invention provides a compound of formula (I) wherein X is a structure of the following formula (i), (ii), (iii), or iv G is O, or S; U is -(CR3R4)n-; W is CH2NHC(=G)R1, CH2NH-het, CH2-G-het, CH2het, C(=O)NHR2; and Y1, Y2 and Y3 are independently CH, or CF. The compounds of the present invention are useful as antibacterial agents.
La présente invention concerne un composé de formule I où X représente une structure de formule i, ii, iii ou iv suivante; G représente O ou S; U représente -(CR3R4)n-; W représente CH2NHC(=G)R1, CH2NH-het, CH2-G-het, CH2het, C(=O)NHR2; et Y1, Y2 et Y3 représentent chacun indépendamment CH ou CF. Les composés selon la présente invention peuvent être employés en tant qu'agents antibactériens.
Gao Hongwu
Gordeev Mikhail
Josyula Vara Prasad Venkata Nagendra
Luehr Gary Wayne
Renslo Adam Robert
Pfizer Products Inc.
Smart & Biggar
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