Benzoxazoles useful in the treatment of inflammation

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 263/57 (2006.01) A61K 31/423 (2006.01) A61K 31/4439 (2006.01) A61K 31/497 (2006.01) A61P 11/06 (2006.01) A61P 29/00 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2620899

There is provided the use of a compound of formula (I),wherein Y, W1 to W4, Z1 to Z4 and R have meanings given in the description, and pharmaceutically- acceptable salts thereof, for the manufacture of a medicament for the treatment of a disease in which inhibition of the activity of a member of the MAPEG family is desired and/or required, and particularly in the treatment of inflammation.

La présente invention concerne l'utilisation d'un composé représenté par la formule (I), dans laquelle Y, W1 à W4, Z1 à Z4 et R sont tels que dans les descriptions, et des sels de ces composés répondant aux normes pharmaceutiques, pour la fabrication d'un médicament destiné au traitement d'une maladie dans laquelle l'inhibition de l'activité d'un élément de la famille MAPEG est recherchée et/ou requise et, en particulier dans le traitement d'une inflammation.

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