Benzoxazolinones

Details Benzoxazolinones Benzoxazolinones

C - Chemistry, Metallurgy

07

D

260/263, 260/311

C07D 263/58 (2006.01) C07D 413/06 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01)

Patent

CA 1208220

ABSTRACT The invention relates to compounds of the formula: Image in which R represents hydrogen or a lower alkyl radical and R1 and R2 separately represent hydrogen, a lower alkyl, cycloalkyl or benzyl radical, or represent, together with the nitrogen atom to which they are bonded, a heterocyclic radical such as a morpholino, 4-(pyrimidin-2-yl)-piperazinyl or 4-phenylpiperazinyl the phenyl radical of which being optionally substituted by halogen, lower alkoxy or trifluoromethyl, having CNS activity and particularly hypnotic properties. Moreover the compounds inwhich R1 and R2 are hydrogen can be used in the treatment of heart failure.

441918

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