Benzoyl peroxide compositions and methods of use

Details Benzoyl peroxide compositions and methods of use Benzoyl peroxide compositions and methods of use

A - Human Necessities

61

K

A61K 8/35 (2006.01) A61K 8/36 (2006.01) A61K 31/192 (2006.01)

Patent

CA 2600547

Solutions of benzoyl peroxide, in one or more solvents are provided that are suitable for direct topical application to the skin of a user or can be formulated into a product that is suitable for topical application to the skin of a user. In embodiments, the solutions include benzoyl peroxide and optionally additional active or inactive ingredients, and a solvent or mixture of solvents in which the benzoyl peroxide is prepared as a clear solution at 25~ C. Methods of using the solutions are also described. Product formulations such as emulsion are also described. The solutions and product formulations can increase the efficacy and percutaneous absorption of benzoyl peroxide.

L'invention concerne des solutions de peroxyde de benzoyle, dans un ou plusieurs solvants, adaptées pour une application directe par voie topique sur la peau d'un utilisateur, ou pouvant être formulées dans un produit adapté pour être appliqué par voie topique sur la peau d'un utilisateur. Dans certains modes de réalisation, les solutions contiennent du peroxyde de benzoyle et éventuellement des ingrédients supplémentaires actifs ou inactifs, et un solvant ou un mélange de solvants dans lequel le peroxyde de benzoyle est préparé de manière à obtenir une solution claire à 25 °C. L'invention concerne également des méthodes d'utilisation des solutions. L'invention concerne en outre des formulations de produits, par exemple des émulsions. Les solutions et les formulations de produits peuvent augmenter l'efficacité et l'absorption percutanée du peroxyde de benzoyle.

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