Benzoyl urea compound

Details Benzoyl urea compound Benzoyl urea compound

C - Chemistry, Metallurgy

07

D

167/211, 260/261

C07D 213/643 (2006.01) A61K 9/14 (2006.01) C07D 237/14 (2006.01) C07D 239/34 (2006.01)

Patent

CA 1294963

ABSTRACT OF THE DISCLOSURE A benzoyl urea compound having the formula: Image (I) wherein X is a halogen atom, a nitro group or a trifluoromethyl group, provided that when Y is a nitro group, X is a halogen atom or a nitro group, Y is a hydrogen atom, a halogen atom, a nitro group or a trifluoromethyl group, Z1 is a halogen atom or a tri- fluoromethyl, Z2 is a hydrogen atom or a halogen atom and A is a nitrogen atom, or the formula Image (II) wherein each of X1 and X2 is a hydrogen atom, a halogen atom or a nitro group, provided that when Y is a nitro group, X1 is a hydrogen atom, Y is a hydrogen atom, a halogen atom, a nitro group or a trifluoromethyl group, and Z is a hydrogen atorn, a halogen atom or a trifluoromethyl group, characterized in that its average particle size is not larger than 1 µ m. The present invention provides a benzoyl urea compound (I) or (II) having an improved absorbability through the gut.

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