Benzoylguanidine derivatives as medicaments

Details Benzoylguanidine derivatives as medicaments Benzoylguanidine derivatives as medicaments

C - Chemistry, Metallurgy

07

C

C07C 279/22 (2006.01) A61K 31/165 (2006.01) A61K 31/275 (2006.01) A61K 31/33 (2006.01) C07D 209/08 (2006.01) C07D 215/14 (2006.01) C07D 217/02 (2006.01) C07D 217/16 (2006.01) C07D 241/42 (2006.01) C07D 263/56 (2006.01) C07D 295/13 (2006.01) C07D 295/32 (2006.01) C07D 307/34 (2006.01) C07D 307/46 (2006.01) C07D 307/56 (2006.01) C07D 307/78 (2006.01) C07D 307/79 (2006.01) C07D 307/80 (2006.01) C07D 307/82 (2006.01) C07D 311/58 (2006.01) C07D 311/96 (2006.01) C07D 317/54 (2006.01) C07D 317/60 (2006.01) C07D 33

Patent

CA 2196763

Guanidine derivatives of formula (I) wherein R1 is hydrogen, hydroxy(lower)alkyl, protected hydroxy(lower)alkyl, acyl(lower)alkoxy, acyl(lower)alkenyl, or acyl, and R2 is ar(lower)alkenyl; aryl substituted with two suitable substituents; indenyl, indanyl, dihydrobenzocycloheptenyl, di(or tetra or hexa or octa or deca)hydronaphthyl, cyclopentenyl, dihydrothienyl, dihydrofuryl or heterobicyclic group, each of which may have suitable substituent(s); lower alkylthienyl; mono(or di)halothienyl; mono(or di or tri)halo(lower)alkylthienyl; acylthienyl; halofuryl; or mono(or di or tri)halo(lower)alkylfuryl; and a pharmaceutically acceptable salt thereof, which is useful as a medicament.

L'invention se rapporte à des dérivés de guanidine de la formule (I) dans laquelle R?1¿ représente hydrogène, hydroxy-alkyle(inférieur), hydroxy-alkyle(inférieur) protégé, acyle-alcoxy(inférieur), acyle-alcényle(inférieur), ou acyle, et R?2¿ représente ar alcényle(inférieur); aryle substitué par deux substituants appropriés; indényle, indanyle, dihydrobenzocycloheptényle, di(ou tétra ou hexa ou octa ou déca)hydronaphtyle, cyclopentényle, dihydrothiényle, un groupe dihydrofuryle ou hétérobicyclique, chacun d'eux pouvant être un ou des substituants appropriés; alkylthiényle inférieur; mono (ou di)halothiényle; mono(ou di ou tri)halo alkylthiényle(inférieur); acylthiényle; halofuryle; ou mono(ou di ou tri)halo alkylefuryle(inférieur). L'invention se rapporte également à un sel pharmaceutiquement acceptable de ces dérivés qui est utilisé comme médicament.

Affiliated with

Also associated with

Rating

Benzoylguanidine derivatives as medicaments does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Benzoylguanidine derivatives as medicaments, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Benzoylguanidine derivatives as medicaments will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2063029