Benzoylpyridazines

Details Benzoylpyridazines Benzoylpyridazines

C - Chemistry, Metallurgy

07

D

C07D 273/04 (2006.01) A61K 31/50 (2006.01) A61K 31/501 (2006.01) A61P 11/06 (2006.01) A61P 19/10 (2006.01) C07D 237/04 (2006.01) C07D 401/12 (2006.01)

Patent

CA 2349232

The invention relates to benzoyl pyridazine derivatives of formula (I), wherein R1, R2, R3 and Q have the meaning defined in claim 1. Said derivatives have a phosphodiesterase IV inhibiting effect and can be used in the treatment of osteoporosis, tumors, cachexia, atherosclerosis, rheumatoid arthritis, multiple sclerosis, diabetes mellitus, inflammatory processes, allergies, asthma, autoimmune diseases and AIDS.

L'invention concerne des dérivés de benzoylpyridazines de formule (I), dans laquelle R?1¿, R?2¿, R?3¿ et Q ont la signification indiquée dans la revendication 1. Ces composés exercent une action inhibitrice sur la phosphodiestérase IV et peuvent servir au traitement de l'ostéoporose, de tumeurs, de la cachexie, de l'athérosclérose, de l'arthrite rhumatoïde, de la sclérose en plaques, du diabète sucré, de processus inflammatoires, d'allergies, de l'asthme, de maladies auto-immunes et du SIDA.

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