C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/14 (2006.01) A61K 31/496 (2006.01) A61K 31/506 (2006.01) A61K 31/5377 (2006.01) A61P 35/00 (2006.01) C07D 401/04 (2006.01) C07D 405/14 (2006.01) C07D 413/14 (2006.01)
Patent
CA 2293714
Novel compounds of Formula (1.0) are disclosed. Also disclosed is a method of inhibiting farnesyl protein transferase function and therefore inhibiting the abnormal growth of cells. The method comprises administering a compound of formula (1.0) to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammal such as a human being.
La présente invention concerne de nouveaux composés représentés par la formule (1.0). La présente invention concerne également un procédé d'inhibition de la fonction de farnésyl protéine transférase et donc d'inhibition de la croissance anormale des cellules. Le procédé consiste à administrer un composé de la formule (1.0) à un système biologique. Le procédé inhibe, en particulier, la croissance anormale des cellules chez un mammifère tel que l'homme.
Baldwin John J.
Cooper Alan B.
Doll Ronald J.
Ganguly Ashit
Girijavallabhan Viyyoor M.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Pharmacopeia Inc.
Schering Corporation
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