Benzyl sulfonamide derivatives as androgen receptor antagonists

Details Benzyl sulfonamide derivatives as androgen receptor antagonists Benzyl sulfonamide derivatives as androgen receptor antagonists

C - Chemistry, Metallurgy

07

D

C07D 215/22 (2006.01) C07D 215/38 (2006.01) C07D 311/18 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 407/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2524434

The present invention is directed to 6-benzylsulfonamido-quinoline/chromene derivatives of formula (I) with the definitions of R1, R2, Z, A and B according to the description, to their use as androgen antagonists, and to formulations containing these androgen antagonists.

La présente invention se rapporte à des dérivés de 6-benzylsulfonamido-quinoléine/chromène de la formule (I), dans laquelle les définitions de R?1¿, R?2¿, Z, A et B sont telles que données dans la description, à leur utilisation comme antagonistes des androgènes, ainsi qu'à des formulations contenant ces antagonistes des androgènes.

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