Benzylbenzene derivatives and methods of use

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 309/10 (2006.01) A61K 31/351 (2006.01) A61P 3/10 (2006.01) C07D 405/12 (2006.01) C07D 407/12 (2006.01)

Patent

CA 2697349

Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by SGLT inhibition.

L'invention propose des composés ayant un effet inhibiteur sur le SGLT co-transporteur du glucose dépendant du sodium. L'invention propose également des compositions pharmaceutiques, des procédés de préparation des composés, des intermédiaires de synthèse et des procédés d'utilisation des composés, indépendamment ou en combinaison avec d'autres agents thérapeutiques, pour traiter des maladies et des affections sur lesquelles l'inhibition du SGLT ont une incidence.

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