Benzylether amine compounds useful as ccr-5 antagonists

Details Benzylether amine compounds useful as ccr-5 antagonists Benzylether amine compounds useful as ccr-5 antagonists

C - Chemistry, Metallurgy

07

D

C07D 207/14 (2006.01) C07D 207/08 (2006.01) C07D 211/38 (2006.01) C07D 211/42 (2006.01) C07D 211/44 (2006.01) C07D 211/46 (2006.01) C07D 211/52 (2006.01) C07D 211/58 (2006.01) C07D 211/62 (2006.01) C07D 211/66 (2006.01) C07D 213/53 (2006.01) C07D 213/82 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 471/10 (2006.01)

Patent

CA 2543913

The present invention relates to compounds which are CCR-5 receptor antagonists of the general formula (I) wherein R1, R2, R3, R4, Ra, Rb, Rc, Rd, X, m and n are as defined herein. The invention further comprises pharmaceutical compositions comprising such compounds, as well as the use of such compounds to treat CCR-5 mediated disorders.

La présente invention concerne des composés qui sont des antagonistes des récepteurs CCR-5, de formule générale (I), dans laquelle R?1¿, R?2¿, R?3¿, R?4¿, R?a¿, R?b¿, R?c¿, R?d¿, X, m et n sont tels que définis dans les revendications. L'invention concerne également des compositions pharmaceutiques comprenant lesdits composés, ainsi que l'utilisation desdits composés pour traiter des troubles médiés par les CCR-5.

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