Benzylether and benzylamino beta-secretase inhibitors for...

A - Human Necessities – 61 – K

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A61K 31/195 (2006.01)

Patent

CA 2540452

The present invention is directed to compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.

L'invention concerne des composés qui sont des inhibiteurs de l'enzyme bêta-sécrétase et qui sont utiles dans le traitement de maladies dans lesquelles l'enzyme bêta-sécrétase est impliquée, comme la maladie d'Alzheimer. L'invention concerne également des compositions pharmaceutiques comprenant lesdits composés et l'utilisation de ces derniers et desdites compositions dans le traitement des maladies dans lesquelles l'enzyme bêta-sécrétase est impliquée.

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