Benzylidene-thiazolidinediones and analogues and their use...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 277/34 (2006.01) A61K 31/4166 (2006.01) A61K 31/42 (2006.01) A61K 31/426 (2006.01) A61K 31/4439 (2006.01) A61P 29/00 (2006.01) C07D 233/40 (2006.01) C07D 233/42 (2006.01) C07D 233/96 (2006.01) C07D 261/12 (2006.01) C07D 277/20 (2006.01) C07D 277/36 (2006.01) C07D 401/06 (2006.01) C07D 401/10 (2006.01) C07D 403/10 (2006.01) C07D 405/10 (2006.01) C07D 417/06 (2006.01) C07D 417/10 (2006.01)

Patent

CA 2384194

The present invention relates to certain substituted heterocycles of Formula (I) which may be useful in the treatment of diseases related to uncontrolled proliferation, such as lymphoma, Hodgkin's Disease, leukemia, breast cancer, prostate cancer or cancers in general; and inflammation, such as osteoarthritis, rheumatoid arthritis, Crohn's Disease or Inflammatory Bowel Disease.

La présente invention concerne certains hétérocycles substitués représentés par la formule (I). Ces hétérocycles peuvent s'avérer efficaces contre, d'une part des affections liées à prolifération non contrôlée (lymphomes, maladie de Hodgkin, leucémie, cancer du sein, de la prostate, cancers en général, etc.), et d'autre part des maladies inflammatoires (arthrose, polyarthrite rhumatoïde, maladie de Crohn, maladie intestinale inflammatoire, etc.).

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