C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 207/44 (2006.01) A61K 31/40 (2006.01)
Patent
CA 2286174
A compound which is a 2-(1H-pyrrol-2-yl)-5[(2H-pyrrol-2-ylidene)methyl]-1H- pyrrole of formula (I), wherein R1 is hydrogen or C1-C5 alkyl; R2 is a C1-C5 alkyl; or a pharmaceutically acceptable salt thereof, is useful as an immunomodulating agent and for treating adult-T-cell leukemia-lymphoma.
L'invention concerne un composé qui est un 2-(1H-pyrrol-2-yl)-5[(2H-pyrrol-2-ylidène)méthyl]-1H-pyrrole de formule (I), dans laquelle R1 représente hydrogène ou alkyle C¿1?-C¿5?; R2 représente alkyle C¿1?-C¿5?; ou un sel pharmaceutiquement acceptable de celui-ci, ce composé pouvant être utilisé comme immunomodulateur et comme traitement de la leucémie/du lymphome à cellules T de l'adulte.
Bargiotti Alberto
Colotta Francesco
D'alessio Roberto
Ferrari Mario
Isetta Anna Maria
Pharmacia Italia Spa
Smart & Biggar
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