Benzylphenyl cyclohexane derivatives and methods of use

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 35/50 (2006.01) A61K 31/047 (2006.01) A61K 31/085 (2006.01) A61K 31/12 (2006.01) A61K 31/222 (2006.01) A61P 3/10 (2006.01) C07C 43/23 (2006.01) C07C 43/253 (2006.01) C07C 49/83 (2006.01) C07C 69/21 (2006.01)

Patent

CA 2707909

Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by SGLT inhibition.

L'invention concerne des composés ayant un effet inhibiteur sur le cotransporteur de glucose dépendant du sodium SGLT. L'invention propose également des compositions pharmaceutiques, des procédés de préparation des composés, des intermédiaires synthétiques, et des procédés d'utilisation des composés, indépendamment et en combinaison avec d'autres agents thérapeutiques, pour traiter des maladies et affections qui sont altérées par une inhibition du SGLT.

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