Benzylpyrimidines

Details Benzylpyrimidines Benzylpyrimidines

C - Chemistry, Metallurgy

07

D

260/262.5

C07D 239/48 (2006.01) C07D 207/325 (2006.01) C07D 207/327 (2006.01) C07D 211/56 (2006.01)

Patent

CA 1059127

ABSTRACT OF THE DISCLOSURE Benzyl pyrimidine derivatives of the formula: Image (I) wherein R1 and R2 each independently represent an amino, optionally C1-3-alkyl- substituted pyrrolo, -NHR3, -N(R3)2, -NHR4 or -N(R3)(R4) group, R3 represents a C1-4-alkyl group, R4 represents an acyl group, derived from a lower aliphatic carboxylic or sulphonic acid, and Z represents a hydrogen, chlorine or bromine atom, a piperidino group or a group R3, OR3 or -N(R3)2, and their salts, are disclosed as well as processes for their manufacture. The compounds(I) and their salts possess antibacterial activity.

242038

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