C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 213/75 (2006.01) A61K 31/18 (2006.01) A61K 31/44 (2006.01) A61P 7/02 (2006.01) C07C 311/16 (2006.01) C07C 311/18 (2006.01) C07C 311/19 (2006.01) C07C 311/46 (2006.01) C07D 213/81 (2006.01) C07D 295/18 (2006.01) C07D 295/185 (2006.01) C07D 409/12 (2006.01)
Patent
CA 2392576
Novel .beta.-amino acid-, aspartic acid- and diaminopropionic-based compounds of the general formula A-Q-D-E-G-J-X wherein A, Q, D, E, G, J and X have the meanings given in the description, their salts and compositions related thereto having activity against mammalian factor Xa are disclosed. The compounds are useful in vitro or in vivo for preventing or treating coagulation disorders.
La présente invention concerne des composés à base d'acides .beta.-aminés, aspartiques et diaminopropioniques représentés par la formule générale A-Q-D-E-G-J-X, certains de leurs sels et des compositions s'y rapportant, tous actifs contre le facteur Xa mammalien. Les éléments A, Q, D, E, G, J et X de cette formule ont la signification qui en est donnée dans la description. Ces composés conviennent particulièrement pour la prévention ou le traitement de troubles de la coagulation, in vitro ou in vivo.
Fan Jingmei
Huang Wenrong
Scarborough Robert
Su Ting
Wang Lingyan
Bereskin & Parr
Fan Jingmei
Huang Wenrong
Millennium Pharmaceuticals Inc.
Scarborough Robert
LandOfFree
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