Beta-amino acid derivatives for treatment of diabetes

Details Beta-amino acid derivatives for treatment of diabetes Beta-amino acid derivatives for treatment of diabetes

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/4155 (2006.01) A61K 31/4178 (2006.01) A61K 31/42 (2006.01) A61K 31/427 (2006.01) A61K 31/433 (2006.01) A61K 31/4439 (2006.01) A61K 31/498 (2006.01) A61K 31/506 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/12 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2712998

Novel heterocyclic compounds of the Formula (I) in which R1, R2, R2', R2', R3, R4, R5, R6, R7 and R8 have the meanings indicated in Claim 1, are activators of glucokinase and can be used for the prevention and/or treatment of Diabetes Typ 1 and 2, obesity, neuropathy and/or nephropathy.

L'invention porte sur de nouveaux composés hétérocycliques de formule (I) dans laquelle: R1, R2, R2', R2', R3, R4, R5, R6, R7 et R8 ont les significations indiquées dans la revendication 1. Ce sont des activateurs de la glucokinase qui peuvent servir à la prévention et/ou au traitement des diabètes de type 1 et 2, de l'obésité, des neuropathies et/ou des néphropathies.

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