Beta-amino heterocyclic dipeptidyl peptidase inhibitors for...

Details Beta-amino heterocyclic dipeptidyl peptidase inhibitors for... Beta-amino heterocyclic dipeptidyl peptidase inhibitors for...

C - Chemistry, Metallurgy

07

D

C07D 211/36 (2006.01) A61K 31/495 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2478389

The present invention is directed to compounds which are inhibitors of the dipeptidyl peptidase-IV enzyme ("DP-IV inhibitors") and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.

L'invention concerne des composés qui sont des inhibiteurs de la dipeptidyl peptidase-IV (<= inhibiteurs de DP IV <= ) et qui sont utiles pour le traitement ou la prévention de pathologies dans lesquelles la dipeptidyl peptidase joue un rôle, telles que le diabète, en particulier le diabète de type 2. L'invention concerne également des compositions pharmaceutiques contenant ces composés, et l'utilisation de ces composés et de ces compositions pour la prévention ou pour le traitement de pathologies dans lesquelles la dipeptidyl peptidase-IV joue un rôle.

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