C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/4365 (2006.01) A61K 31/437 (2006.01) A61P 15/00 (2006.01) C07D 209/00 (2006.01) C07D 221/00 (2006.01) C07D 333/00 (2006.01) C07D 487/04 (2006.01) C07D 491/048 (2006.01) C07D 495/04 (2006.01)
Patent
CA 2409715
The present invention relates to novel .beta.-carboline derivatives of the general formula (I), wherein all the variables are as described within the specification, useful as phosphodiesterase inhibitors. The present invention further relates to use of the described derivatives for the treatment of diseases and conditions related to PDE, for example male erectile dysfunction.
La présente invention se rapporte à de nouveaux dérivés .beta.-carboline représentés par la formule générale (I), dans laquelle toutes les variables sont décrites dans la description associée; ces dérivés s'avèrent utiles en tant qu'inhibiteurs de la phosphodiestérase. La présente invention se rapporte également à l'utilisation de ces dérivés pour le traitement de maladies et d'affections associées à la phosphodiestérase, telles que par exemple la dysérection.
Macielag Mark J.
Sui Zhihua
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Ortho-Mcneil Pharmaceutical Inc.
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