C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/242, 260/328
C07D 335/02 (2006.01) A61K 31/38 (2006.01) A61K 31/70 (2006.01) C07C 323/09 (2006.01) C07C 323/62 (2006.01) C07C 333/04 (2006.01) C07H 13/00 (2006.01) C07H 13/04 (2006.01) C07H 15/14 (2006.01) C07H 15/203 (2006.01)
Patent
CA 2000769
ABSTRACT OF THE DISCLOSURE The present invention relates, by way of novel industrial products, to the .beta.-D-phenylthioxyloside compounds of the formula Image (I) in which: - X represents a sulfur atom or an oxygen atom; - R1, R2 and R3, which are identical or different, each represent a hydrogen atom, a nitro group, a cyano group, a group -CO-R (in which R represents a C1-C4 alkyl group or a trifluoromethyl group), an amino group, an acetamido group (NHCOCH3), a C1-C4 alkoxy group, a trifluoromethyl group or a phenyl group substituted by one or more cyano, nitro or trifluoromethyl groups, it being possible for X1 and R2, taken together, to form, with the phenyl group to which they are bonded, a .beta.-naphthalenyl group which is unsubstituted or substituted by one or more cyano, nitro or trifluoromethyl groups; and - Y represents the hydrogen atom or an aliphatic acyl group. These compounds are useful as therapeuticals, especially as venous antithrombotics.
Bajgrowicz Jerzy
Barberousse Veronique
Bellamy Francois
Millet Jean
Renaut Patrice
Fournier Industrie Et Sante
Macrae & Co.
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