C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 16/42 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2303421
The present invention relates to polynucleotide and polypeptide molecules for zampl, a member of the beta-defensin family. The polypeptides, and polynucleotides encoding them, exhibit anti-microbial activity and may be used in the study or treatment of microbial infections. The present invention also includes antibodies to the zampl polypeptides.
La présente invention a trait à des molécules de polynucléotides et de polypeptides de zamp1, qui constitue un nouveau membre de la famille des défensines bêta. Les polypeptides, et les polynucléotides qui codent pour ceux-ci, présentent une activité antimicrobienne et peuvent être utilisés pour étudier ou traiter des infections microbiennes. La présente invention a également trait à des anticorps dirigés contre les polypeptides de zamp1.
Adler David
Baindur Nand
Beigel-Orme Stephanie
Holloway James L.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Zymogenetics Inc.
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