Beta-defensins

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/47 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2389256

The present invention relates to polynucleotide and polypeptide molecules for zamp3 and zamp4, novel members of the .beta.-defensin family. The polypeptides, and polynucleotides encoding them, are useful in the study or treatment of microbial infections. The present invention also includes antibodies to the zamp3 or zamp4 polypeptides.

La présente invention concerne des molécules polynucléotidiques et polypeptidiques pour zamp3 et zamp4, de nouveaux membres de famille des .beta.-défensines. Les polypeptides, et les polynucléotides codant ceux-ci, servent à l'étude et au traitement d'infections microbiennes. La présente invention concerne également des anticorps contre les polypeptides zamp3 et zamp4.

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