Beta glycolipids as immuno-modulators

Details Beta glycolipids as immuno-modulators Beta glycolipids as immuno-modulators

A - Human Necessities

61

K

A61K 31/70 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2630935

The present invention relates to a process for the modulation of the Th1/Th2 cell balance toward anti-inflammatory cytokine producing cells, in a subject suffering from an immune related disorder. The process of the invention comprises the step of increasing the intracellular, extra-cellular or serum level of a naturally occurring .beta.-glycolipid in a subject in need thereof. The invention further relates to methods for the treatment of a subject suffering from an immune-related disease. Therapeutic compositions and method for the preparation of these compositions are also provided

La présente invention concerne un procédé pour la modulation de l'équilibre cellulaire Th1/Th2 de cellules produisant des cytokines anti-inflammatoires, chez un sujet souffrant d~un trouble de nature immunitaire. Le procédé de l'invention comprend l'étape consistant à augmenter le taux intracellulaire, extracellulaire ou sérique d'un .beta.-glycolipide d'origine naturelle chez un sujet le nécessitant. L'invention concerne en outre des procédés pour le traitement d'un sujet souffrant d'une maladie de nature immunitaire. La présente invention concerne en outre des compositions thérapeutiques et un procédé pour la préparation de ces compositions.

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