.beta.-lactam antibiotics

Details .beta.-lactam antibiotics .beta.-lactam antibiotics

C - Chemistry, Metallurgy

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C07D 205/085 (2006.01) C07D 401/00 (2006.01) C07D 417/06 (2006.01) C07D 471/04 (2006.01) C07F 7/08 (2006.01) C07F 7/10 (2006.01) C07F 9/6558 (2006.01) C12P 17/10 (2006.01)

Patent

CA 1338670

.beta.-Lactams having a sulfonic acid substituent in the 1- position and an amine function in the 3-position and having the formula: Image wherein R1 is H or acyl derived from a carboxylic acid; R2 is H or alkoxy; R3 and R4, the same or different, are H, alkyl, cycloalkyl, phenyl or substituted phenyl, or one of R3 and R4 is H and the other is alkoxycarbonyl, alken-1-yl, alkyn-1-yl, 2-phenylethenyl or 2-phenylethynyl; and X is H or SO3X is SO3?M? wherein M?is a cation, and the use of said .beta.-lactams as antibiotics.

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