.beta.-lactam compound and preparing thereof

C - Chemistry – Metallurgy – 07 – F

Patent

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260/336.5

C07F 7/10 (2006.01) C07D 205/08 (2006.01) C07F 7/18 (2006.01)

Patent

CA 1269388

Abstract of the Disclosure The present invention relates to .beta.-lactam compound having the general formula (I): Image (I) wherein R1 is a protective group for hydroxy group, R2, R3 and R4 are selected from a lower alkyl group of C1 to C4, phenyl group and aralkyl group and a process for preparing thereof which comprises reacting enolsilylether having the general forumal (III): Image (III) wherein R1, R2, R3 and R4 are as above, with chlorosulfonylisocyanate and then reducing the obtained product. .beta.-Lactam compound of the present invention is a useful intermediate for preparing carbapenem .beta.-lactam compound.

485099

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