Beta-lactam synthesis

Details Beta-lactam synthesis Beta-lactam synthesis

C - Chemistry, Metallurgy

07

D

C07D 205/08 (2006.01)

Patent

CA 2610442

The present invention is directed to a process for the preparation of .beta.- lactams. Generally, an imine is cyclocondensed with a ketene acetal or enolate to form the Beta-lactam product in a "one pot" synthesis, this process is generally performed at a higher temperature than conventional processes.

La présente invention concerne un procédé de préparation de ß-lactames. De manière générale, une imine est soumise à une cyclocondensation avec un cétène acétal ou un énolate en vue de la formation du produit ß-lactame dans une synthèse monotope, ce procédé étant généralement réalisé à une température supérieure à celle des procédés classiques.

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